Ischemic in anteroseptal leads (ISCAS) is a type of electrocardiogram (ECG) finding that indicates a possible lack of blood flow and oxygen to the heart muscle in the anteroseptal region, which includes leads V1-V4.
ISCAS can be asymptomatic, meaning that the individual may not experience any noticeable symptoms. However, some individuals may experience symptoms such as chest pain, shortness of breath, palpitations, and dizziness.
When reviewing an ECG for ISCAS, it is important to pay attention to the presence of ST-T wave changes that are localized to the anteroseptal leads. Other things to pay attention to include the presence of T wave inversions, ST segment depression or elevation, and the morphology of the QRS complexes.
If ISCAS is suspected, further testing such as stress testing, echocardiography, or cardiac catheterization may be recommended to determine the extent of the ischemia and if there is an underlying cardiovascular condition that requires treatment.